Stem Cell Biology and Biobanking

The incidence of traumatic injuries is estimated as > 500,000 new patients annually in the world.[1] Post-traumatic brachial plexus injury can result in complete sensory and motor function loss which is challenging for reversal of the damage, but not untreatable. Few therapeutic options like neurotization by total and hemi-contralateral nerve root transfer are available with limited benefits.[2] Re-innervation of denervated targets can be achieved by regeneration of injured axons or by collateral branching of undamaged axons in the vicinity. Nevertheless, these mechanisms do not provide for satisfactory functional recovery, especially after severe injuries.[1] Stem cell therapy (SCT) holds promise in tissue regeneration.